GANGLIOSIDE MICELLES AS A DELIVERY SYSTEM FOR HYDROPHOBIC DRUGS

DESCRIPCION


This invention discloses water soluble pharmaceutical compositions including at least one therapeutically active substance and at least one compound selected from the sialoglycosphingolipids, the glycosphingolipids or a mixture of sialoglicosphingolipids and glycosphingolipids, in which at least one of the therapeutically active substances is a drug with hydrophobic characteristics. In
particular, sterile compositions for i.v. administration, composed of nano-glycosphingolipids micelles or modified glycosphingolipids, which can be coated with albumin in a noncovalent form and which allow transport and controlled release of highly hydrophobic molecules are disclosed.

 

https://patentscope.wipo.int/search/es/detail.jsf?docId=CA94579849&tab=NATIONALBIBLIO

 

Nº de solicitud: 2797295
Oficina: CA